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KMID : 0364820180540030244
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Korean Journal of Microbiology
2018 Volume.54 No. 3 p.244 ~ p.253
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Antimicrobial activity by Paenibacillus elgii DS381 and its antimicrobial substances against microbial residents on human skin and pathogenic bacteria
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Lee Da-Sol
Song Hong-Gyu
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Abstract
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This study was carried out to evaluate effects of antimicrobialsubstances produced by isolated soil bacteria. Among twothousands of bacterial isolates Paenibacillus elgii DS381 exhibitedhigh antimicrobial activities against several microbialresidents on human skin and pathogenic bacteria. DS381showed 15.3~26.0 mm inhibition zone diameter against all targetbacteria and yeast in agar well diffusion test. Antimicrobialpeptide produced by DS381 indicated low minimum inhibitoryconcentration (0.039?5.000 mg/ml). DS381 produced biosurfactantsuch as lipopeptide, and surface tension of culture supernatantof DS381 reduced from 60.0 to 40.3 mN/m. DS381 also showed1.56 ± 0.13 U/ml of chitinase activity. These results suggestthat Paenibacillus elgii DS381 may be utilized as an efficientbiocontrol agent against some important human skin microbesand pathogenic bacteria.
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KEYWORD
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Paenibacillus elgii DS381, antimicrobial activity, antimicrobial peptide, biosurfactant
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